26 results
A New Natural Defense Against Airborne Pathogens
- David Edwards, Anthony Hickey, Richard Batycky, Lester Griel, Michael Lipp, Wes Dehaan, Robert Clarke, David Hava, Jason Perry, Brendan Laurenzi, Aidan K. Curran, Brandon J. Beddingfield, Chad J. Roy, Tom Devlin, Robert Langer
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- Journal:
- QRB Discovery / Volume 1 / 2020
- Published online by Cambridge University Press:
- 07 July 2020, e5
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- 2020
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We propose the nasal administration of calcium-enriched physiological salts as a new hygienic intervention with possible therapeutic application as a response to the rapid and tenacious spread of COVID-19. We test the effectiveness of these salts against viral and bacterial pathogens in animals and humans. We find that aerosol administration of these salts to the airways diminishes the exhalation of the small particles that face masks fail to filter and, in the case of an influenza swine model, completely block airborne transmission of disease. In a study of 10 human volunteers (5 less than 65 years and 5 older than 65 years), we show that delivery of a nasal saline comprising calcium and sodium salts quickly (within 15 min) and durably (up to at least 6 h) diminishes exhaled particles from the human airways. Being predominantly smaller than 1 μm, these particles are below the size effectively filtered by conventional masks. The suppression of exhaled droplets by the nasal delivery of calcium-rich saline with aerosol droplet size of around 10 μm suggests the upper airways as a primary source of bioaerosol generation. The suppression effect is especially pronounced (99%) among those who exhale large numbers of particles. In our study, we found this high-particle exhalation group to correlate with advanced age. We argue for a new hygienic practice of nasal cleansing by a calcium-rich saline aerosol, to complement the washing of hands with ordinary soap, use of a face mask, and social distancing.
Genome-wide association study of response to cognitive–behavioural therapy in children with anxiety disorders
- Jonathan R. I. Coleman, Kathryn J. Lester, Robert Keers, Susanna Roberts, Charles Curtis, Kristian Arendt, Susan Bögels, Peter Cooper, Cathy Creswell, Tim Dalgleish, Catharina A. Hartman, Einar R. Heiervang, Katrin Hötzel, Jennifer L. Hudson, Tina In-Albon, Kristen Lavallee, Heidi J. Lyneham, Carla E. Marin, Richard Meiser-Stedman, Talia Morris, Maaike H. Nauta, Ronald M. Rapee, Silvia Schneider, Sophie C. Schneider, Wendy K. Silverman, Mikael Thastum, Kerstin Thirlwall, Polly Waite, Gro Janne Wergeland, Gerome Breen, Thalia C. Eley
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- Journal:
- The British Journal of Psychiatry / Volume 209 / Issue 3 / September 2016
- Published online by Cambridge University Press:
- 02 January 2018, pp. 236-243
- Print publication:
- September 2016
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Background
Anxiety disorders are common, and cognitive–behavioural therapy (CBT) is a first-line treatment. Candidate gene studies have suggested a genetic basis to treatment response, but findings have been inconsistent.
AimsTo perform the first genome-wide association study (GWAS) of psychological treatment response in children with anxiety disorders (n = 980).
MethodPresence and severity of anxiety was assessed using semi-structured interview at baseline, on completion of treatment (post-treatment), and 3 to 12 months after treatment completion (follow-up). DNA was genotyped using the Illumina Human Core Exome-12v1.0 array. Linear mixed models were used to test associations between genetic variants and response (change in symptom severity) immediately post-treatment and at 6-month follow-up.
ResultsNo variants passed a genome-wide significance threshold (P=5×10–8) in either analysis. Four variants met criteria for suggestive significance (P<5×10–6) in association with response post-treatment, and three variants in the 6-month follow-up analysis.
ConclusionsThis is the first genome-wide therapygenetic study. It suggests no common variants of very high effect underlie response to CBT. Future investigations should maximise power to detect single-variant and polygenic effects by using larger, more homogeneous cohorts.
Contributors
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- By Agoston T. Agoston, Syed Z. Ali, Mahul B. Amin, Daniel A. Arber, Pedram Argani, Sylvia L. Asa, Rebecca N. Baergen, Zubair W. Baloch, Andrew M. Bellizzi, Kurt Benirschke, Allen Burke, Kenneth B. Calder, Karen L. Chang, Rebecca D. Chernock, Wang Cheung, Thomas V. Colby, Byron P. Croker, Ronald A. DeLellis, Edward F. DiCarlo, Ralph C. Eagle, Hormoz Ehya, Brett M. Elicker, Tarik M. Elsheikh, Robert E. Fechner, Linda D. Ferrell, Melina B. Flanagan, Douglas B. Flieder, Christopher S. Foster, Lillian Gaber, Karuna Garg, Kim R. Geisinger, Ryan M. Gill, Eric F. Glassy, David J. Glembocki, Zachary D. Goodman, Robert O. Greer, David J. Grignon, Gerardo E. Guiter, Kymberly A. Gyure, Ian S. Hagemann, Michael R. Henry, Jason L. Hornick, Ralph H. Hruban, Phyllis C. Huettner, Peter A. Humphrey, Olga B. Ioffe, Edward C. Klatt, Michael J. Klein, Ernest E. Lack, James N. Lampros, Lester J. Layfield, Robin D. LeGallo, Kevin O. Leslie, James S. Lewis, Virginia A. LiVolsi, Alberto M. Marchevsky, Anne Marie McNicol, Mitra Mehrad, Elizabeth Montgomery, Cesar A. Moran, Christopher A. Moskaluk, George J. Netto, G. Petur Nielsen, Robert D. Odze, Arthur S. Patchefsky, James W. Patterson, Elizabeth N. Pavlisko, John D. Pfeifer, Celeste N. Powers, Richard A. Prayson, Anja C. Roden, Victor L. Roggli, Andrew E. Rosenberg, Sherif Said, Margie A. Scott, Raja R. Seethala, Carlie S. Sigel, Jan F. Silverman, Bruce R. Smoller, Edward B. Stelow, Nora C. J. Sun, Mark W. Teague, Satish K. Tickoo, Thomas M. Ulbright, Paul E. Wakely, Jun Wang, Lawrence M. Weiss, Mark R. Wick, Howard H. Wu, Rhonda K. Yantiss, Charles Zaloudek, Yaxia Zhang, Xiaohui Sheila Zhao
- Edited by Mark R. Wick, University of Virginia, Virginia A. LiVolsi, University of Pennsylvania School of Medicine, John D. Pfeifer, Washington University School of Medicine, St Louis, Edward B. Stelow, University of Virginia, Paul E. Wakely, Jr
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- Book:
- Silverberg's Principles and Practice of Surgical Pathology and Cytopathology
- Published online:
- 13 March 2015
- Print publication:
- 26 March 2015, pp vii-x
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Contributors
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- By Syed Z. Ali, Rose Anton, Güliz A. Barkan, Natasha Berg, Joan F. Cangiarella, Richard L. Cantley, Rosa M. Dávila, Tarik M. Elsheikh, Paolo Gattuso, Blythe K. Gorman, Umesh Kapur, Walid E. Khalbuss, Lester J. Layfield, Pascale Levine, Xiaoqi Lin, Amy A. Lo, Shahla Masood, Claire W. Michael, Ritu Nayar, Ajit Paintal, Anil V. Parwani, Telma C. Pereira, Vijaya B. Reddy, Marilin Rosa, Reda S. Saad, Jan F. Silverman, Aylin Simsir, Luan D. Truong, Julianne M. Ubago, Eva M. Wojcik, Lourdes R. Ylagan, Mohammad M. Yousef, Jing Zhai
- Edited by Paolo Gattuso, Rush University, Chicago, Vijaya B. Reddy, Rush University, Chicago, Shahla Masood
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- Book:
- Differential Diagnosis in Cytopathology
- Published online:
- 05 December 2014
- Print publication:
- 04 December 2014, pp viii-x
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- By Osvaldo P. Almeida, Rebecca Anglin, Vivek Benegal, Margaret N. Berry, Nash N. Boutros, Henry Brodaty, Alan S. Brown, Monte S. Buchsbaum, William Burke, Kim Burns, Stanley V. Catts, Vibeke S. Catts, Jennifer M. Connolly, David L. Copolov, Louisa Degenhardt, Stewart L. Einfeld, Anthony Feinstein, Matt P. Galloway, Bangalore N. Gangadhar, Wayne Hall, Malcolm Hopwood, Michael D. Jibson, Ripu D. Jindal, David J. Kavanagh, Sophie Kavanagh, Matcheri S. Keshavan, Ennapadam S. Krishnamoorthy, Rajeev Kumar, Alexander F. Kurz, Nicola T. Lautenschlager, Edward C. Lauterbach, Leslie Lester-Burns, Lyn-May Lim, Jeffrey C. L. Looi, Michael Mazurek, Serge A. Mitelman, Ramon Mocellin, Bryan Mowry, Kim T. Mueser, Anand K. Pandurangi, Eric M. Pihlgren, Seethalakshmi Ramanathan, Patricia I. Rosebush, Perminder S. Sachdev, Richard D. Sanders, Vandana Shashi, Arabella Smith, Sergio E. Starkstein, Ezra S. Susser, Rajiv Tandon, Jagadisha Thirthalli, Bruce J. Tonge, Julian Trollor, Dennis Velakoulis, Mark Walterfang, Jane Zhang
- Edited by Perminder S. Sachdev, University of New South Wales, Sydney, Matcheri S. Keshavan
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- Secondary Schizophrenia
- Published online:
- 05 August 2011
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- 04 February 2010, pp vii-xii
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15 - The Government's Role in Innovation
- John M. Deutch, Massachusetts Institute of Technology, Richard K. Lester, Massachusetts Institute of Technology
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- Making Technology Work
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- 10 December 2009
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- 10 November 2003, pp 246-262
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Summary
The fundamental purpose of national government is to protect and improve the public welfare. Governments seek to defend national security (in the broadest sense), work to improve the economic well-being of their citizens, and protect public health, safety, and natural resources. Technological advance plays a vital role in each of these domains. The government, therefore, has a strong interest in encouraging technological innovation. But exactly what should this role be? How can the government be involved most effectively in the development and implementation of new technologies? What policy instruments can and should the government use to intervene in the innovation process?
The pace and direction of innovation depends on the research and development (R&D) activity of the economy. As Figure 15.1 shows, each year U.S. industry and government both devote large amounts of resources to R&D.
The R&D activity reported in these statistics is only part of the innovation process, of course. As we have seen, inventing and developing technology is just one of the steps involved. Invention must be followed by implementation, which is a complex, uncertain, and costly process. Our focus in this chapter is primarily on R&D, especially the R&D that is funded by the U.S. government at a current rate of roughly $75 billion per year. By any measure, this is a lot of money. But is it too much? Or not enough?
10 - Natural Gas
- John M. Deutch, Massachusetts Institute of Technology, Richard K. Lester, Massachusetts Institute of Technology
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- Making Technology Work
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- 10 December 2009
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- 10 November 2003, pp 164-180
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Summary
Natural gas will be the world's most important source of new primary energy supplies during the next two decades. Consumption of the fuel worldwide is projected to double by the year 2020. In the United States, natural gas is currently the second most important fuel after coal, accounting for almost a quarter of all energy consumed, and the U.S. Energy Information Administration projects that domestic consumption in 2020 will be 50% higher than today. Much of this growth will occur in the electricity sector. More than 90% of additions to U.S. electricity generating capacity over the next decade will be gas-fired. Natural gas is also an attractive residential and commercial heating source (most new single-family homes use gas heating) as well as an important industrial fuel.
The emergence of natural gas as the fuel of choice for electricity generation in the United States stands in sharp contrast to the situation less than two decades ago. After vigorous growth earlier in the twentieth century, U.S. gas consumption peaked in the early 1970s and continued to decline until the middle part of the 1980s (see Figure 10.1). During part of this period, the use of natural gas by electric utilities was actually prohibited by the federal government on the grounds that it should not be “wasted” by combustion in utility boilers but rather conserved for more important uses such as heating homes and as feedstock for chemical plants. In this chapter, we will examine the reasons for this striking reversal.
16 - Conclusions
- John M. Deutch, Massachusetts Institute of Technology, Richard K. Lester, Massachusetts Institute of Technology
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- Making Technology Work
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- 10 December 2009
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- 10 November 2003, pp 263-266
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Summary
In the academic world, technology-oriented students mainly learn in “stove pipes” defined by established disciplines in the natural and social sciences and in engineering. This compartmentalization is understandable because the foundations of the disciplines are most easily learned separately and best taught by specialists. One must learn calculus, chemical kinetics, microeconomics, or system control before being able to address the complex relationships between these subjects that may arise in practical applications of technology. The result, however, is that students learn about the pieces of a problem rather than the whole. Moreover the learning is typically a solitary activity, and rarely depends upon the cooperation of a group.
Yet real problems are an inseparable mix of technological, economic, environmental, and political factors. As we have seen, successful application of technology frequently requires the synthesis of all these considerations. When this synthesis is absent or is not credible, the technology will fail to live up to its potential and may fail completely. And successful syntheses require individuals to work together to bring different skills to bear on the problem. We teach individual disciplines, but the resolution of most real problems requires that different disciplines be jointly brought to bear. It is as if people were taught how to play the individual musical instruments of an orchestra and then expected immediately to perform a symphony.
Students understand that they will face these sorts of problems in the course of their professional careers.
3 - Solar Thermal, Windpower, and Photovoltaic Technologies
- John M. Deutch, Massachusetts Institute of Technology, Richard K. Lester, Massachusetts Institute of Technology
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- Making Technology Work
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- 10 December 2009
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- 10 November 2003, pp 17-48
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Summary
Many experts believe that nonrenewable fuels, in particular oil and gas, will eventually become so scarce and therefore so expensive that they will no longer be practical large-scale energy sources. Moreover, the use of coal and other fossil fuels imposes major environmental burdens. Therefore, it is prudent to develop energy technologies based on renewable energy sources and introduce them commercially if and when they become economically competitive.
There are many renewable energy technologies to consider. First are those that rely on natural terrestrial forces: wind, geothermal, hydropower, and tidal power. Second, there are technologies that rely directly on solar energy. These include solar hot water heating, solar thermal electric conversion (either in solar “power towers” or in the more exotic form of solar power satellites), and photovoltaics. Some terrestrial energy sources can be regarded as indirect forms of solar energy. For example, solar ponds and ocean thermal energy conversion (OTEC) rely on solar-heating-induced temperature gradients. Similarly, solar heating of the atmosphere drives the winds. Biomass, another important renewable energy source, can also be regarded as an indirect form of solar energy.
We shall not analyze all these technologies in this chapter. Rather our purpose is to describe a process for evaluating and comparing competing technologies. We consider three important renewable energy technologies in some detail: solar hot water heating, wind energy, and photovoltaics. In each case the task is to evaluate the technical and economic feasibility of substituting the renewable technology for traditional energy sources.
5 - Controlling Acid Rain from Coal-fired Power Plants
- John M. Deutch, Massachusetts Institute of Technology, Richard K. Lester, Massachusetts Institute of Technology
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- Making Technology Work
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- 10 December 2009
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- 10 November 2003, pp 66-80
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Summary
The acid rain case considered in this chapter is an example of good government decision making. The history of federal acid rain control legislation demonstrates that it is possible for the government to arrive at an environmental control strategy that minimizes the costs of bringing about reductions, and that is at least consistent with analyses of the costs and benefits of alternative courses of action. The rational approach to decision making in this case is very different from the story of the federal gasohol program presented in chapter 2.
The public is greatly concerned about the environmental impact of emissions from coal-fired electric power plants. An important question is how much of society's resources should be spent on reducing the environmental impact of electricity generated from coal. As discussed in the preceding chapter, there are many different consequential emissions that must be considered, including carbon dioxide (CO2), sulfur dioxide (SO2), oxides of nitrogen (NOx), particulates, heat, and solid and liquid wastes.
In this chapter we consider the gaseous emissions of SO2 and NOx. These emissions form acids when combined with moisture in the atmosphere. The possible result is the phenomenon of “acid rain,” in which rain falling at a considerable distance from the originating plant (perhaps across a national border) has high acidity. This high acidity rain can harm forests, vegetation, lakes, and the fish the lakes contain; indeed, acid rain impacts the entire ecology.
9 - Nuclear Power and Weapons Proliferation
- John M. Deutch, Massachusetts Institute of Technology, Richard K. Lester, Massachusetts Institute of Technology
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- Making Technology Work
- Published online:
- 10 December 2009
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- 10 November 2003, pp 154-163
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Summary
The discussion in the previous two chapters vividly illustrates the complexity of real world applications of nuclear reactor technology and its associated fuel cycle systems. We considered several issues that have brought this once promising technology to its knees: Economics, safety, and the environmental concerns surrounding waste management and disposal. In this chapter, we discuss the proliferation of nuclear weapons, another important problem related to the civilian use of nuclear power. Simply stated, commercial nuclear power carries with it a risk that technologies and materials from the nuclear fuel cycle will be misused for making nuclear bombs. There has been significant opposition to nuclear power on these grounds, and especially to nuclear exports to countries thought to be interested in acquiring nuclear weapons capability. In this chapter, we discuss the origin of these concerns, the history of how the proliferation issue arose, and the steps that have been taken by the international community to reduce the proliferation risks of nuclear power and, hence, to remove this obstacle to the peaceful application of nuclear technology.
Making Bombs
Nuclear fission weapons are made from either plutonium or highly enriched uranium (HEU). When a relatively small quantity of either of these materials (on the order of 10kg) is compressed by a modest amount of chemical explosives, an uncontrolled fission chain reaction can occur, releasing tremendous amounts of energy.
Contents
- John M. Deutch, Massachusetts Institute of Technology, Richard K. Lester, Massachusetts Institute of Technology
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- Making Technology Work
- Published online:
- 10 December 2009
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- 10 November 2003, pp vii-viii
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2 - Gasohol
- John M. Deutch, Massachusetts Institute of Technology, Richard K. Lester, Massachusetts Institute of Technology
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- Making Technology Work
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- 10 December 2009
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- 10 November 2003, pp 9-16
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Summary
This chapter considers the question: Should national energy policy encourage the growing of corn to produce gasohol? Gasohol is the product of the conversion of corn or sugar to ethanol (ethyl alcohol), which is employed as a gasoline additive. Ordinarily, the term gasohol refers to a mixture of 10% ethanol and 90% gasoline. The idea of gasohol in current U.S. policy is simple: Use ethanol from corn to displace a portion of the gasoline for motor vehicles, thereby substituting a renewable energy source (corn) for a depletable energy source (petroleum). Because the purpose of government support for gasohol is to substitute for petroleum, we focus on the petroleum fuel and undertake a careful energy balance comparing the petroleum needed to produce gasohol with the petroleum that the gasohol displaces. The point is to identify the net petroleum displaced by gasohol.
TECHNICAL ASPECTS OF GASOHOL
The production of ethanol from corn requires several steps. First, the corn must be grown; then the starch (long-chain macromolecules made up of six-carbon sugars) must be separated from the corn. The starch is then hydrolyzed to glucose, which in turn is fermented to form ethanol. Finally, the ethanol is separated from the fermentation liquor by distillation.
Each of these steps requires energy. Much of the energy required for growing the corn comes from sunlight. But the intensive form of agriculture practiced in the United States, which results in high crop yields, requires a considerable amount of expensive premium fuels for fertilizers, farming, and harvesting.
6 - Greenhouse Gases and Global Warming
- John M. Deutch, Massachusetts Institute of Technology, Richard K. Lester, Massachusetts Institute of Technology
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- Making Technology Work
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- 10 December 2009
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- 10 November 2003, pp 81-108
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Summary
Since the beginning of the industrial age, growing quantities of gases have been released into the atmosphere with the ability to trap sunlight and thus with the potential to cause an increase in the mean global temperature. A temperature increase of just a few degrees will lead to climate changes that have the potential to cause irreversible ecological impacts with enormous accompanying economic and social dislocations. The purpose of this chapter is to describe how the United States and other nations are dealing with this complex issue.
The quantity of gases for which human activity is responsible is small relative to both the total atmospheric inventory and the fluxes from natural sources such as plant growth and decay. As Figure 6.1 shows, the flux of carbon released today by the burning of fossil fuels is a very modest fraction of the carbon fluxes that are naturally exchanged between the atmosphere and the upper layers of the ocean and between the atmosphere and the terrestrial biosphere. But those natural flows had previously been in close balance, and the human contribution is growing rapidly (see Figure 6.2). This anthropogenic perturbation has the potential to destroy the delicate radiative balance that maintains the Earth's surface temperature.
Global warming is perhaps the most complex technology issue on the public policy agenda. The tasks of understanding the underlying science, predicting the climate impact of greenhouse gas emissions, and verifying these predictions all present extraordinary challenges.
Frontmatter
- John M. Deutch, Massachusetts Institute of Technology, Richard K. Lester, Massachusetts Institute of Technology
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- Making Technology Work
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- 10 December 2009
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- 10 November 2003, pp i-vi
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4 - Electricity from Coal
- John M. Deutch, Massachusetts Institute of Technology, Richard K. Lester, Massachusetts Institute of Technology
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- Making Technology Work
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- 10 December 2009
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- 10 November 2003, pp 49-65
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Summary
Coal is by far the most plentiful of conventional fossil fuels. The world's total coal resources have been estimated to be as much as 10,000 billion tons – enough, in principle, to meet all of the world's energy needs for 1000 years at current rates of consumption. Coal, moreover, is widely distributed. The largest known resources are in Russia and other nations of the former Soviet Union, the United States, and China, but many other countries in every continent have sizeable deposits.
In the United States, coal is the largest energy-producing industry, accounting for nearly a third of all domestic energy production and almost a quarter of all energy consumed. The industry is a net exporter, and employs about 80,000 miners in 26 states.
The most important use of coal today in the United States and around the world is for electricity generation (see Figure 4.1). Of the billion tons of coal consumed annually in the United States, 90% is used in electric power stations, and these coal-fired plants generate more than half of the nation's electricity (see Table 4.1).
These figures make clear that coal will be an important fuel source and industry for many decades. However, there is growing awareness of the health and, especially, the environmental problems associated with its use. In this chapter we examine the technical and economic aspects of coal-fired electricity generation.
11 - Safety and Risk: Examples from the Liquefied Natural Gas and Nuclear Industries
- John M. Deutch, Massachusetts Institute of Technology, Richard K. Lester, Massachusetts Institute of Technology
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- Book:
- Making Technology Work
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- 10 December 2009
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- 10 November 2003, pp 181-193
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Summary
The application of almost all new technologies involves some degree of risk to public health and safety and the environment, and these risks must be systematically considered. For some technologies the risks are primarily confined to the manufacturing process. In other cases, it is the users who incur the main risks. In still other cases, the risks are externalized – that is, they are borne by people who are not direct beneficiaries of the technology either as suppliers or users. Where the new technology is displacing an existing product or process, the net risk to society may be either increased or reduced. A few technologies have the potential to cause harm on a large scale as a result of a single event. The probability of such events may be extremely low, but they cannot be ruled out entirely. Special methods have been developed to evaluate these low-probability, high-consequence risks. This chapter briefly introduces these methods, using nuclear power plants and liquefied natural gas facilities as examples. We also consider the question of public attitudes toward health and safety risks. Innovators and safety regulators alike need to understand how the public perceives risks, how these perceptions are formed, and what causes them to change.
LIQUEFIED NATURAL GAS
There are many areas of the world where gas exists in great abundance, either in free deposits, for example, in New Zealand, Indonesia, and Algeria, or associated with oil reserves, for example, in Nigeria and Saudi Arabia.
12 - Synthetic Fuels
- John M. Deutch, Massachusetts Institute of Technology, Richard K. Lester, Massachusetts Institute of Technology
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- Making Technology Work
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- 10 December 2009
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- 10 November 2003, pp 194-204
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Summary
For the foreseeable future the world will rely on oil and gas to meet much of its energy requirements, especially for transportation. Many countries will need to import much, and in some cases, all of the oil they consume. This dependence on oil and on oil imports prompts an interest in exploring technologies that can produce gas and liquid fuels from more plentiful and accessible raw materials.
Conventional liquid petroleum products such as gasoline, diesel fuel, and kerosene are easily obtained by upgrading crude oil in petroleum refineries. Synthetic fuels (often also referred to as synfuels) are oil and gas substitutes that are produced from more plentiful hydrocarbon resources by complex chemical processing. The raw materials for synthetic fuels are tar sands, shale, and coal. The cost of producing synthetic fuels from these resources defines a “shadow price” for oil and gas products obtained from conventional oil and gas resources. If the price of fuel from conventional sources were to rise above the cost of producing synthetic fuels, the market would be expected to switch to producing synthetic fuels in quantity. The price increase might occur either because of cartel action by oil exporting countries, or because of the progressive depletion of oil and gas resources.
This chapter introduces the technical aspects of some of the principal synthetic fuel production processes. The cost of producing synthetic fuels is also discussed.
Preface
- John M. Deutch, Massachusetts Institute of Technology, Richard K. Lester, Massachusetts Institute of Technology
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- Book:
- Making Technology Work
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- 10 December 2009
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- 10 November 2003, pp ix-x
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Summary
This book grows out of a multidisciplinary course we have taught to MIT graduate and undergraduate students for over a decade. The course, “Application of Technology,” is designed to introduce our students to the complex task of applying new technologies for economic, social or environmental purposes. Our goal in the course – and in this book – is to present insights, approaches, and analytical tools that are useful in such situations. This is an especially important subject for students educated in the sciences or engineering disciplines. Although most of these students will encounter complex problems of technology application in the course of their professional careers, their education today is focused on problems within their particular technical discipline. The solution of such problems may be crucial to technology invention and development but only a small part of what is required for successful technology application.
A central theme of this book is that students in the sciences and engineering should recognize the importance of moving away from thinking solely about the creation of new technology to thinking also about its responsible and effective application. Finding the right balance between these two ways of thinking is a fundamental challenge for technology practitioners – and for educators in science and engineering as well.
A second and related challenge is to move from working within the boundaries of a single discipline to integrating across disciplines.
7 - Nuclear Power and Its Fuel Cycle
- John M. Deutch, Massachusetts Institute of Technology, Richard K. Lester, Massachusetts Institute of Technology
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- Making Technology Work
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- 10 December 2009
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- 10 November 2003, pp 109-133
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Summary
No technological system more dramatically illustrates the central themes of this book – the complexity of real world applications of technology and the pitfalls of ignoring the social, political, and environmental dimensions of innovation – than nuclear power. Once widely seen as an energy source of almost unlimited potential, nuclear power is today expanding in just a handful of countries. In most countries with operating nuclear power stations there are no plans to build additional nuclear plants, and some countries have made formal decisions to phase out their existing reactors as quickly as possible.
Despite its limited growth prospects, nuclear power is today playing an important role around the world with nearly 440 plants supplying 17% of the world's electricity. In some countries, the level of dependence is much higher. France derives 76% of its electricity from nuclear power, and other heavily nuclear-reliant countries include Belgium, Japan, and South Korea (see Table 7.1). The world's largest nuclear power program is in the United States, where more than 100 plants provide 20% of the nation's electricity. Keeping these plants operating safely, reliably, and economically is a vital task for private firms and governments around the world. But with few new nuclear plants being built, almost every energy forecast projects a gradual decline in the nuclear share of world electricity supplies.